My mold infected family has been taking grapefruit seed extract (GSE) as a natural anti-fungal treatment for the past year. I believe it has been one of the main health supplements, along with hyperbaric oxygen therapy (HBOT) that has helped put us all on the road to recovery. Our decision to start taking GSE was made after I had done many hours of research and also from a recommendation made to us by our great holistic doctor friends who have treated many people with GSE.
My research has helped validate our decision by leading me to various scientific studies on grapefruit seed extract that prove that it has incredible anti-fungal, anti-bacteria, and anti-viral properties. GSE is a natural antibiotic and antifungal medication. Internally grapefruit seed extract can help with gastrointestinal disorders, diarrhea, food poisoning, parasites, candida yeast infections, thrush, oral infections, colds and flu, sore throats, strep throat, and sinusitis. It can also be used to treat skin conditions-nail fungus, cold sores, athletes foot, rashes, acne, etc.
Grapefruit is a citrus fruit. GSE is made by mixing grapefruit seeds and pulp into a thick, yellow, acidic liquid that is normally mixed with vegetable glycerin to reduce the bitterness. It is sold either as a liquid concentrate or in tablets. Grapefruit seed extract is taken by mouth for bacterial, viral, and fungal infections, including yeast infections.
If you research the internet, you will find many alternative health doctors, coaches and bloggers who claim that GSE is an awesome treatment for many illnesses and diseases such as the ones mentioned above. This is great news, but it is also important that we look at the various studies that have been done in clinical settings to help verify these testimonials.
What I have discovered is that there are quite a few studies that seem to back up these claims, which I would like to share with you below.
Recent testimonials report grapefruit-seed extract, or GSE (Citricidal) to be effective against more than 800 bacterial and viral strains, 100 strains of fungus, and a large number of single and multicelled parasites.(2)
Dr. Leo Galland, M.D. of New York City, considers the availability of grapefruit seed extract to be “…a major therapeutic breakthrough for patients with chronic parasitic and yeast infections…” He reports treatment failures in only two cases out of 297.
Dr. Galland had said, “It would be hard to overstate the value of GSE to my medical practice. It has no inherent toxicity. For the past year I have used GSE in the treatment of intestinal parasitism and chronic candidiasis with excellent results. In the treatment of candidiasis it appears as effective as nystatin, caprylic acid, and other non-absorbed intestinal antifungal agents.
Many drug sensitive individuals find GSE to be much better tolerated than other antifungal preparations, and I have several patients in whom this product alone helped control chronic candidiasis when no other medication was tolerated or effective. In the treatment of intestinal protozoan infections, (Giardia lamblia and Entamoeba histolytica) GSE has for the most part been more effective than metronidazole and other prescription antiprotozoan drugs.”
The U.S. National Library of Medicine said this about grapefruit seed extract:
“Grapefruit juice is used for high cholesterol, “hardening of the arteries” (atherosclerosis), cancer, a skin disease called psoriasis, and for weight loss and obesity.
Grapefruit seed extract is taken by mouth for bacterial, viral, and fungal infections, including yeast infections.
Grapefruit oil is applied to the skin for muscle fatigue, hair growth, toning the skin, and for acne and oily skin. It is also used for the common cold and flu (influenza).
Grapefruit seed extract is applied to the skin as a facial cleanser, first-aid treatment, remedy for mild skin irritations, and as a vaginal douche for vaginal yeast infections (candidiasis). It is also used as an ear or nasal rinse for preventing and treating infections; as a gargle for sore throats; a dental rinse for preventing gingivitis and promoting healthy gums; and as a breath freshener.
Some people inhale grapefruit vapors to help the body retain water, for headache, stress, and depression. Grapefruit seed extract vapor has also been inhaled for the treatment of lung infections.”(1)
The University of Georgia evaluated grapefruit seed extract as a disinfectant in tests against E. Coli, Salmonella sps., and Staph aureus. Microbiologist Roger Wyatt, Ph.D., reported,
“Our studies indicate excellent potential for these products(GSE). …The toxicological that I have reviewed indicated that this product and the active ingredient poses very low toxicity. As you know this is important because most disinfectants that are currently used in either animal or human environments have moderate to high toxicity and extreme care must be exercised when these products are used. The lack of any significant toxicological properties of (GSE) is also impressive when one views the efficacy data where extremely small concentrations of the product can be used with marked beneficial results.”
Dr. Wyatt further stated, “In view of the reports that we have discussed, the wide spectrum of activity that (GSE) offers(antiviral, antibacterial; Gram+ and Gram-, antimycotic, and antiprotozoan) will undoubtedly aid in its acceptability.”
In 2001, a study titled, “Effects of 33% grapefruit extract on the growth of the yeast–like fungi, dermatopytes and molds,” had examined the influence of grapefruit extract on the yeast-like fungi strains–Candida albicans growth. Researchers found that 33% grapefruit extract exert a potent antifungal activity against the yeast like fungi strains and had low activity against dermatophytes and moulds.(2)
A 2002 research paper titled, “The effectiveness of processed grapefruit-seed extract as an antibacterial agent,” had shown the drops of concentrated grapefruit-seed extract were tested for antibacterial properties against a number of gram-positive and gram-negative organisms.The GSE was consistently antibacterial against all of the biotypes tested, with susceptibility zone diameters equal to or greater than 15 mm in each case.
The researchers in the study concluded, “Our preliminary data thus suggest an antibacterial characteristic to GSE that is comparable to that of proven topical antibacterials. Although the GSE appeared to have a somewhat greater inhibitory effect on gram-positive organisms than on gram-negative organisms, its comparative effectiveness against a wide range of bacterial biotypes is significant.”(3)
A 2005 study paper, “The effectiveness of grapefruit (Citrus paradisi) seeds in treating urinary tract infections,” suggests an antibacterial characteristic of dried or fresh grapefruit seeds (C. paradisi) when taken at a dosage of 5 to 6 seeds every 8 hours, that is comparable to that of proven antibacterial drugs.”(3)
Many of us who suffer from a mold illness and subsequent fungal and/or bacterial infections have serious inflammation issues. The good news is that studies such as “Helichrysum and Grapefruit ExtractsBoost Weight Loss in Overweight Rats Reducing Inflammation,” show that Helichrysum and grapefruit extracts might be used as complement hypocaloric diets in weight loss treatment. Both extracts helped to reduce weight gain, hyperinsulinemia, and IR, improved inflammation markers, and decreased the HFS diet-induced oxidative stress in insulin-resistant rats. PMID:25599391 (4)
Mold Safe Solutions Conclusion:
My own family’s experience with grapefruit seed extract (GSE) and the testimony of several reputable alternative health doctors, coaches and bloggers, help prove that it may be an effective treatment for your mold illness and/or fungal infection. The subsequent scientific studies that have been done over the years help validate our claims by showing the actual research behind this most wonderful and ancient seed.
Now it is up to you to decide if it is a worthy addition to your own supplement protocol.
If you have taken GSE or have a question, please leave a comment below.
Moe Bedard is the founder and CEO of Mold Safe Solutions. A full-service Indoor Air Quality (IAQ) company specializing in property water damage, mold inspections, consultations, and mold remediation. If you need help with a project, please call Mold Safe Solutions at 760-818-6830.